Thyroid-like follicular carcinoma of the kidney

From Libre Pathology
Revision as of 04:56, 27 October 2014 by Michael (talk | contribs)
Jump to navigation Jump to search

Thyroid-like follicular carcinoma of the kidney, also thyroid-like follicular renal cell carcinoma, is a recently described rare kidney tumour.

It is considered an emerging entity by the Vancouver modification of the 2004 WHO classification of renal neoplasia.[1]

General

  • Extremely rare - less than 15 cases reported in the literature.[1]
  • Large age range (29-83 years old).

Gross

  • Solid, brown and well circumscribed.

Microscopic

Features:[1]

  • Thyroid follicule-like structures - both microfollicular and/or microfollicular. **Contain dense-appearing eosinophilic material.
  • Encapuslated.
  • Nuclei round and regular with prominent nucleoli (ISUP nucleolar grade 2 or 3).

DDx:

IHC

Features:[1]

  • TTF-1 -ve.
  • Thyroglobulin -ve.
  • CK7 +ve/-ve.
  • PAX8 +ve/-ve.

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Srigley, JR.; Delahunt, B.; Eble, JN.; Egevad, L.; Epstein, JI.; Grignon, D.; Hes, O.; Moch, H. et al. (Oct 2013). "The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia.". Am J Surg Pathol 37 (10): 1469-89. doi:10.1097/PAS.0b013e318299f2d1. PMID 24025519.
Retrieved from "https://librepathology.org/w/index.php?title=Thyroid-like_follicular_carcinoma_of_the_kidney&oldid=34454"