Prostatic stromal tumour of uncertain malignant potential

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Prostatic stromal tumour of uncertain malignant potential, usually abbreviated STUMP,[1] is a rare lesion of the prostatic stroma which cannot be definitively classified as benign or malignant.

It is also known as prostatic stromal proliferation of uncertain malignant potential (abbreviated PSPUMP).[2]

General

  • Rare.

Microscopic

Features:

Note:

  • May be seen with glandular abnormalities.[3]

DDx:

IHC

Features:[1]

  • ER +ve.
  • PR +ve.
  • Desmin +ve/-ve.
  • CD34 +ve.

See also

References

  1. 1.0 1.1 1.2 De Berardinis, E.; Busetto, GM.; Antonini, G.; Giovannone, R.; Di Placido, M.; Magliocca, FM.; Di Silverio, A.; Gentile, V. (2012). "Incidental prostatic stromal tumor of uncertain malignant potential (STUMP): histopathological and immunohistochemical findings.". Urologia 79 (1): 65-8. doi:10.5301/RU.2012.9099. PMID 22388992.
  2. Gaudin, PB.; Rosai, J.; Epstein, JI. (Feb 1998). "Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases.". Am J Surg Pathol 22 (2): 148-62. PMID 9500215.
  3. Nagar, M.; Epstein, JI. (Jun 2011). "Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP).". Am J Surg Pathol 35 (6): 898-903. doi:10.1097/PAS.0b013e318214f2f2. PMID 21572264.