Miscellaneous ovarian tumours
Revision as of 06:32, 25 July 2014 by Michael (talk | contribs) (→Ovarian small cell carcinoma of the hypercalcemic type)
The article collects miscellaneous ovarian tumours, as per the WHO classification.[1]
Ovarian small cell carcinoma of the pulmonary type
- See: Small cell carcinoma.
Ovarian small cell carcinoma of the hypercalcemic type
- Abbreviated OSSCHT.
- AKA small cell carcinoma, hypercalcemic type, AKA small cell carcinoma of the ovary, hypercalcemic type.
General
- Hypercalcemia.[2]
- Rare.
Microscopic
Features:[2]
- Small cell carcinoma.
- Follicle-like spaces.
DDx:
- Small cell carcinoma of the lung.
- Small cell carcinoma of the cervix.
- Sertoli-Leydig cell tumour.
- Juvenile granulosa cell tumour.
Images
www:
OSSCHT - low mag. (WC)
OSSCHT - high mag. (WC)
IHC
Features:[3]
- WT-1 +ve.
- TTF-1 -ve.
- HPV -ve.
- p16 +ve/-ve.
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 403. ISBN 978-0781765275.
- ↑ 2.0 2.1 Young, RH.; Oliva, E.; Scully, RE. (Nov 1994). "Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases.". Am J Surg Pathol 18 (11): 1102-16. PMID 7943531.
- ↑ Carlson, JW.; Nucci, MR.; Brodsky, J.; Crum, CP.; Hirsch, MS. (Sep 2007). "Biomarker-assisted diagnosis of ovarian, cervical and pulmonary small cell carcinomas: the role of TTF-1, WT-1 and HPV analysis.". Histopathology 51 (3): 305-12. doi:10.1111/j.1365-2559.2007.02790.x. PMID 17727473.