Subependymoma

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Subependymoma is neuropathology tumour classically found in the fourth ventricle.

General

  • Good prognosis - WHO Grade I.

Gross/radiology

  • Classic location: fourth ventricle.[1]
  • Well demarcated margin.
  • Usu. completely within the ventricle; does not extend into brain (like ependymomas).

Microscopic

Features:[2]

  • Microcysts with bluish material - give a spongy appearance at low magnification.
  • Nuclei cluster.
    • Described as "bundles of flowers".

Negatives.

  • No nuclear pleomorphism, no prominent nucleoli, no mitoses.

Images

www:

See also

References

  1. Hoeffel, C.; Boukobza, M.; Polivka, M.; Lot, G.; Guichard, JP.; Lafitte, F.; Reizine, D.; Merland, JJ.. "MR manifestations of subependymomas.". AJNR Am J Neuroradiol 16 (10): 2121-9. PMID 8585504. http://www.ajnr.org/cgi/reprint/16/10/2121.
  2. 2.0 2.1 URL: http://moon.ouhsc.edu/kfung/jty1/Com05/Com501-2-Diss.htm. Accessed on: 2 June 2011.