Post-inflammatory pigment alteration
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Post-inflammatory pigment alteration, abbreviated PIPA, is benign dermal pigmentation change. It may be either hyperpigmentation or hypopigmentation.[1]
General
Clinical DDx:
Microscopic
Features:
- Perivascular pigment incontinence.
- No melanocytic nests.
- No increase of melanocytes.
DDx:
- Ephilis (freckle).
- Solar lentigo.
Stains
- Fontana-Masson stain +ve.
- Iron stain -ve.
See also
References
- ↑ Cardinali, G.; Kovacs, D.; Picardo, M. (Dec 2012). "Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo.". Ann Dermatol Venereol 139 Suppl 4: S148-52. doi:10.1016/S0151-9638(12)70127-8. PMID 23522630.