Esophageal stricture

Esophageal stricture is usually a clinical diagnosis. Considered broadly, strictures may be benign or malignant.

This article deals primarily with benign stricture of the esophagus or benign esophageal stricture.

General

Strictures in general:

• Malignant - it is the pathologists job to help rule-out these.
• Benign.

Treatment:

• Stenting.
• Endoscopic dilation.
• Surgery.

Microscopic

Features:

• Squamous mucosa with irritation:
  • +/-Keratinization.
  • Intraepithelial lymphocytes.
  • Basal cell hyperplasia.
• Fibrosis (deep) - usually not seen.

DDx:

• GERD.
• Barrett's esophagus.
• Squamous cell carcinoma of the esophagus.
• Adenocarcinoma of the esophagus.

Sign out

ESOPHAGUS, BIOPSY:
- SQUAMOUS MUCOSA WITH BASAL CELL HYPERPLASIA, MILD INTRAEPITHELIAL EDEMA, FOCAL EARLY
  KERATINIZATION AND INTRAEPITHELIAL LYMPHOCYTES.
- SCANT COLUMNAR EPITHELIUM WITH MODERATE CHRONIC INACTIVE INFLAMMATION.
- NEGATIVE FOR INTESTINAL METAPLASIA.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.

See also

• Esophagus.
• Achalasia.