Thrombotic thrombocytopenic purpura

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Thrombotic thrombocytopenic purpura is a type of thrombotic microangiopathy.

It was classically described as the pentad of:[1]

  1. Fever.
  2. Thrombocytopenia.
  3. Microangiopathic hemolytic anemia.
  4. Transient neurologic symptoms.
  5. Renal failure.

Mnemonic: HUS/TTP is a CRAFTY syndrome:[2]

  • CNS symptoms.
  • Renal failure.
  • Anemia - microangiopathic hemolytic anemia.
  • Fever.
  • Thrombocytopenia.
  • Y - no one knows "Y" it occurs.

See also

References

  1. Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 669. ISBN 978-1416031215.
  2. URL: http://www.valuemd.com/mnemonics2.php. Accessed on: 8 November 2010.