Hypertension
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Hypertension is very common and affects multiple organs. Clinically, it is usually classified as primary (idiopathic) and secondary.
Brain
Charcôt-Bouchard aneurysms
General
- AKA miliary aneurysms.
- Intracerebral hemorrhages.
Microscopic
Features:[1]
- Small aneurysms (~300 micrometers) with a fusiform shape.
- Vessel wall changes:
- Early:
- Proliferation of arteriolar smooth muscle
- Late:
- Apoptotic smooth muscle cell death and collagen deposition.
- Early:
Image: C-B aneurysm (ucsf.edu).
Eye
- Blindness.
Heart
- Concentric hypertrophy.
Kidney
- Renal failure.
Features:[2]