Hypertension

Hypertension is very common and affects multiple organs. Clinically, it is usually classified as primary (idiopathic) and secondary.

Brain

Charcôt-Bouchard aneurysms

General

• AKA miliary aneurysms.
• Intracerebral hemorrhages.

Microscopic

Features:

• Small aneurysms (~300 micrometers) with a fusiform shape.
• Vessel wall changes:
  • Early:
    • Proliferation of arteriolar smooth muscle
  • Late:
    • Apoptotic smooth muscle cell death and collagen deposition.

Image: C-B aneurysm (ucsf.edu).

Eye

• Blindness.

Heart

• Concentric hypertrophy.

Kidney

• Renal failure.

See also

• Pulmonary hypertension.
• Vascular disease.

External links

• Microvascular disease (ucsf.edu).