Hypertension

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Hypertension is very common and affects multiple organs. Clinically, it is usually classified as primary (idiopathic) and secondary.

Brain

Charcôt-Bouchard aneurysms

General

Microscopic

Features:[1]

  • Small aneurysms with a fusiform shape.
  • Vessel wall changes:
    • Early:
      • Proliferation of arteriolar smooth muscle
    • Late:
      • Apoptotic smooth muscle cell death and collagen deposition.

Eye

  • Blindness.

Heart

  • Concentric hypertrophy.

Kidney

  • Renal failure.

See also

References

  1. Auer RN, Sutherland GR (December 2005). "Primary intracerebral hemorrhage: pathophysiology". Can J Neurol Sci 32 Suppl 2: S3–12. PMID 16450803.