Histiocytoses
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Histiocytoses, singular histiocytosis, are a rare set of conditions affecting tissue macrophages.
Histiocytoses in a table
Features of histiocytoses:[1]
| Histologic features | EM features | CD68 | S-100 | CD1a | |
|---|---|---|---|---|---|
| Macrophage | epithelioid cells, giant cells | - | + | - | - |
| Erdheim-Chester disease | Touton giant cells | - | + | +/- | - |
| Rosai-Dorfman | Emperipolesis | - | + | + | - |
| Langerhans-histiocytosis | Reniform nuclei, eosinophilic cytoplasm |
Birbeck granules | + | + | + |
Notes:
- EM = electron microscopy.
See also
References
- ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 479. ISBN 978-0781740517.