Henoch–Schönlein purpura

Henoch-Schönlein purpura, abbreviated HSP, a disease that afflicts children.

Pathologically, it can be thought of as the combination of:

1. IgA nephropathy.
2. Leukocytoclastic vasculitis.

Clinical features

The classic triad is:

1. Palpable purpura.
2. Abdominal pain.
3. Arthritis.

Mnemonic NAPA:

• Nephritis.
• Arthralgia/arthritis.
• Palpable purpura.
• Abdominal pain.

Work-up - partial:

• ESR - high.
• Creatinine - high.
• CBC - platelets should be normal or high.
  • Low platelets + purpura think thrombotic microangiopathies (e.g. TTP, HUS).

See also

• Vasculitides.
• Medical kidney diseases.
• Pediatric pathology.