Sjögren syndrome

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Sjögren syndrome, also Sjögren disease, is a disease that keeps rheumatologists busy. Sjögren is also spelled Sjoegren and Sjogren.

General

Clinical - classically:

  • Women in 50s.
  • Dry mouth (xerostomia).
  • Dry eyes (xerophthalmia).

Blood work:[1]

  • ANA +ve.
  • Anti-SSA (Ro) +ve.
  • Anti-SSB (La) +ve.

Microscopic

Features (salivary gland):[1]

  • Lymphocytic infiltration - key feature.
  • +/-Atrophy of salivary gland.
  • +/-Fibrosis.

DDx:

See also

References

  1. ↑ 1.0 1.1 "Information from your family doctor. Sjögren syndrome.". Am Fam Physician 79 (6): 472. Mar 2009. PMID 19323360.
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