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Difference between revisions of "Medical kidney diseases"
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Medical kidney diseases (view source)
Revision as of 18:05, 25 November 2011
, 18:05, 25 November 2011→Primary light microscopy patterns: update
(→Membranoproliferative glomerulonephritis: more, +images) |
(→Primary light microscopy patterns: update) |
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| Line 389: | Line 389: | ||
| '''DDx''' | | '''DDx''' | ||
| '''Image''' | | '''Image''' | ||
|- | |- | ||
|Normal light microscopy | |Normal light microscopy | ||
| Normal histology | | Normal histology | ||
| none | | none | ||
| [[membranous nephropathy]] | | [[membranous nephropathy]], FSGS | ||
| normal kidney, [[minimal change disease]], [[thin glomerular basement membrane disease]], [[Alport syndrome]], early [[membranous nephropathy]] | | normal kidney, [[minimal change disease]], [[thin glomerular basement membrane disease]], [[Alport syndrome]], early [[membranous nephropathy]] | ||
| Image? | | Image? | ||
|- | |- | ||
|[[Membranous nephropathy]] | |Nodular mesangial expansion | ||
| nodular mesangial matrix expansion, no mesangial hypercellularity | |||
| GBM thickening, both afferent and efferent arteriole hyalinized | |||
| diffuse proliferative GN, membranous nephropathy | |||
| [[diabetic nephropathy]], [[idiopathic nodular glomerulosclerosis]], [[amyloidosis]], light chain deposition disease | |||
| [http://commons.wikimedia.org/wiki/File:Nodular_glomerulosclerosis.jpeg (WC)] | |||
|- | |||
|[[Membranous nephropathy]] (MN) | |||
| GBM spikes or pinholes with silver stain, GBM thickening on PAS | | GBM spikes or pinholes with silver stain, GBM thickening on PAS | ||
| +/-mesangial hypercellularity +/-tram-tracking/wireloop GBM | | +/-mesangial hypercellularity +/-tram-tracking/wireloop GBM | ||
| normal light microscopy | | normal light microscopy, light chain deposition disease | ||
| [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic | | [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic (MN); light chain deposition disease ([[plasma cell neoplasm]]) | ||
| | | [http://commons.wikimedia.org/wiki/File:Membranous_nephropathy_-_mpas_-_very_high_mag.jpg (WC)] | ||
|- | |- | ||
|[[Focal segmental glomerulosclerosis]] | |[[Focal segmental glomerulosclerosis]] | ||
| sclerosed glomeruli = mesangial expansion with collagen | | sclerosed glomeruli = mesangial expansion with collagen | ||
| +/-glomerular enlargement, +/- tuft-capsule adhesions | | +/-glomerular enlargement, +/- tuft-capsule adhesions | ||
| [[rapidly progressive glomerulonephritis]], nodular | | [[rapidly progressive glomerulonephritis]], nodular mesangial expansion | ||
| primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]] | | primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]] | ||
| [http://commons.wikimedia.org/wiki/File:Focal_segmental_glomerulosclerosis_-_high_mag.jpg (WC)] | | [http://commons.wikimedia.org/wiki/File:Focal_segmental_glomerulosclerosis_-_high_mag.jpg (WC)] | ||
| Line 423: | Line 423: | ||
| nodular glomerulosclerosis | | nodular glomerulosclerosis | ||
| [[post-infectious glomerulonephritis]], [[MPGN]], [[dense deposit disease]], diffuse proliferative [[lupus nephritis]] (class IV), cryoglobulinemic GN | | [[post-infectious glomerulonephritis]], [[MPGN]], [[dense deposit disease]], diffuse proliferative [[lupus nephritis]] (class IV), cryoglobulinemic GN | ||
| | | [http://commons.wikimedia.org/wiki/File:Membranoproliferative_glomerulonephritis_-_very_high_mag.jpg (WC)] | ||
|- | |- | ||
|[[Rapidly progressive glomerulonephritis]] | |[[Rapidly progressive glomerulonephritis]] | ||
| Line 430: | Line 430: | ||
| [[FSGS]], diffuse proliferative glomerulonephritis | | [[FSGS]], diffuse proliferative glomerulonephritis | ||
| [[AGBM]], [[post-infectious glomerulonephritis]], pauci-immune GN, immune complex diseases ([[lupus nephritis]], [[IgA nephropathy]], others) | | [[AGBM]], [[post-infectious glomerulonephritis]], pauci-immune GN, immune complex diseases ([[lupus nephritis]], [[IgA nephropathy]], others) | ||
| | | [http://en.wikipedia.org/wiki/File:Crescentic_glomerulonephritis_%282%29.jpg (WC)] | ||
|- | |- | ||
|Tubular injury | |Tubular injury | ||