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Difference between revisions of "Thyroid gland"
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→Hürthle cell neoplasm
(→Hürthle cell neoplasm: more) |
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*Some advocate ''total thyroidectomy'' for all Hürthle cell neoplasms, as it is difficult to reliably differentiate adenomas and carcinomas.<ref name=pmid9697901>{{Cite journal | last1 = Wasvary | first1 = H. | last2 = Czako | first2 = P. | last3 = Poulik | first3 = J. | last4 = Lucas | first4 = R. | title = Unilateral lobectomy for Hurthle cell adenoma. | journal = Am Surg | volume = 64 | issue = 8 | pages = 729-32; discussion 732-3 | month = Aug | year = 1998 | doi = | PMID = 9697901 }}</ref> | *Some advocate ''total thyroidectomy'' for all Hürthle cell neoplasms, as it is difficult to reliably differentiate adenomas and carcinomas.<ref name=pmid9697901>{{Cite journal | last1 = Wasvary | first1 = H. | last2 = Czako | first2 = P. | last3 = Poulik | first3 = J. | last4 = Lucas | first4 = R. | title = Unilateral lobectomy for Hurthle cell adenoma. | journal = Am Surg | volume = 64 | issue = 8 | pages = 729-32; discussion 732-3 | month = Aug | year = 1998 | doi = | PMID = 9697901 }}</ref> | ||
*It can be understood as a special type of ''follicular neoplasm'' (including ''follicular adenoma'' and ''follicular carcinoma'').<ref name=Ref_EP104>{{Ref EP|104}}</ref> | *It can be understood as a special type of ''follicular neoplasm'' (including ''[[follicular thyroid adenoma]]'' and ''[[follicular thyroid carcinoma]]'').<ref name=Ref_EP104>{{Ref EP|104}}</ref> | ||
====Adenoma vs. carcinoma==== | ====Adenoma vs. carcinoma==== | ||
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_EP104>{{Ref EP|104}}</ref> | Features:<ref name=Ref_EP104>{{Ref EP|104}}</ref> | ||
*Oncocytes: | *Oncocytes >= 75% of cells: | ||
**Abundant granular, eosinophilic cytoplasm. | **Abundant granular, eosinophilic cytoplasm. | ||
**Round regular nucleus +/- prominent nucleolus. | **Round regular nucleus +/- prominent nucleolus. | ||