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(→Polyarteritis nodosa: more) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features - medium-sized vessels with: | ||
*Inflammatory cells (neutrophils, lymphocytes) within the tunica media. | *Inflammatory cells (neutrophils, lymphocytes) within the tunica media. | ||
*Fibroid necrosis: dead vessel wall - pink anucleate stuff, nuclear debris (black specks of nuclear material). | *Fibroid necrosis: dead vessel wall - pink anucleate stuff, nuclear debris (black specks of nuclear material). | ||
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Image: | Image: | ||
*[http://www.immunologyclinic.com/figure.asp?chap=10&fig=14-05d PAN (immunologyclinic.com)]. | *[http://www.immunologyclinic.com/figure.asp?chap=10&fig=14-05d PAN (immunologyclinic.com)]. | ||
==Microscopic polyangiitis== | |||
===General=== | |||
*Classically MPO-ANCA (p-ANCA) +ve. | |||
===Microscopic=== | |||
Features - small-sized vessels with: | |||
*Inflammatory cells (neutrophils, lymphocytes) within the tunica media. | |||
*Fibroid necrosis: dead vessel wall - pink anucleate stuff, nuclear debris (black specks of nuclear material). | |||
*No granulomas. | |||
==Wegener granulomatosis== | ==Wegener granulomatosis== |
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