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(→Nephrotic syndrome: +link to main) |
(→Patterns - Table: more) |
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| focal sclerosis of gloms | | focal sclerosis of gloms | ||
| +/-interstitial fibrosis | | +/-interstitial fibrosis | ||
| EM | | IF: negative; EM: foot process loss | ||
| nephrotic syndrome | | nephrotic syndrome | ||
| primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]]); unresponsive to steroids, worse prognosis than MCD | | primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]]); unresponsive to steroids, worse prognosis than MCD | ||
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| Gloms with wire loops | | Gloms with wire loops | ||
| mesangial hypercellularity | | mesangial hypercellularity | ||
| EM | | IF: diffuse granular capillary loop IgG, C3, kappa, lambda; EM diffuse subepithelial deposits - spike forming | ||
| nephrotic syndrome | | nephrotic syndrome | ||
| [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic | | [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic | ||
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|- | |- | ||
|[[Minimal change disease]] (MCD) | |[[Minimal change disease]] (MCD) | ||
| EM | | foot process loss on [[EM]] | ||
| usu. none | | usu. none | ||
| EM | | EM: foot process loss | ||
| nephrotic syndrome | | nephrotic syndrome | ||
| primary vs. secondary ([[lymphoproliferative disorder]], NSAIDs); idiopathic responds to steroids | | primary vs. secondary ([[lymphoproliferative disorder]], NSAIDs); idiopathic responds to steroids |
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