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**Most sensitive and specific feature of PRCC.<ref>{{cite journal |author=Granter SR, Perez-Atayde AR, Renshaw AA |title=Cytologic analysis of papillary renal cell carcinoma |journal=Cancer |volume=84 |issue=5 |pages=303?8 |year=1998 |month=October |pmid=9801205 |doi= |url=http://dx.doi.org/10.1002/(SICI)1097-0142(19981025)84:5<303::AID-CNCR6>3.0.CO;2-7}}</ref> | **Most sensitive and specific feature of PRCC.<ref>{{cite journal |author=Granter SR, Perez-Atayde AR, Renshaw AA |title=Cytologic analysis of papillary renal cell carcinoma |journal=Cancer |volume=84 |issue=5 |pages=303?8 |year=1998 |month=October |pmid=9801205 |doi= |url=http://dx.doi.org/10.1002/(SICI)1097-0142(19981025)84:5<303::AID-CNCR6>3.0.CO;2-7}}</ref> | ||
*Highly vascular. | *Highly vascular. | ||
Size criterion: | Size criterion: | ||
*Papillary lesions '''''must''''' be >0.5 cm to be called ''carcinoma''; smaller lesions (<=0.5 cm) are called ''[[papillary adenoma]]s''.<ref name=Ref_GUP288>{{Ref GUP|288}}</ref> | *Papillary lesions '''''must''''' be >0.5 cm to be called ''carcinoma''; smaller lesions (<=0.5 cm) are called ''[[papillary adenoma]]s''.<ref name=Ref_GUP288>{{Ref GUP|288}}</ref> | ||
Clear cell RCC | Mnemonic ''HIP'': '''h'''ighly vascular, '''i'''nterstitial foam cells, '''p'''apillae. | ||
*Papillary: +histiocytes, +intracellular hemosiderin, [[CK7]]+. | |||
DDx: | |||
*Clear cell RCC. | |||
**Papillary: +histiocytes, +intracellular hemosiderin, [[CK7]]+. | |||
*[[Metanephric adenoma]] - esp. solid PRCC type 1. | |||
====Histological subtyping==== | ====Histological subtyping==== |
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