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*May look like eosinophilic variant of chromophobe RCC -- this is the main DDx. | *May look like eosinophilic variant of chromophobe RCC -- this is the main DDx. | ||
**A comparison based on histomorphology: ''[[Kidney_tumours#Tabular_comparison_of_oncocytoma_and_chromophobe_RCC|Tabular comparison between ChRCC & oncocytoma]]''. | **A comparison based on histomorphology: ''[[Kidney_tumours#Tabular_comparison_of_oncocytoma_and_chromophobe_RCC|Tabular comparison between ChRCC & oncocytoma]]''. | ||
*** | ***Oncocytoma typically has: no perinuclear clearing, no raisinoid nuclei, no binucleation. | ||
**IHC may be useful to differentiate (CK7: oncocytoma = cytoplasm +ve, chromophobe = cell membrane +ve). | **IHC may be useful to differentiate (CK7: oncocytoma = cytoplasm +ve, chromophobe = cell membrane +ve). | ||
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