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Difference between revisions of "Extramammary Paget disease"
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Extramammary Paget disease (view source)
Revision as of 14:12, 2 September 2011
, 14:12, 2 September 2011+IHC from - breast Paget's
m (→DDx) |
(+IHC from - breast Paget's) |
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*Benign Toker cell hyperplasia. | *Benign Toker cell hyperplasia. | ||
*[[Malignant melanoma]]. | *[[Malignant melanoma]]. | ||
*Bowen disease | *[[Bowen disease]]. | ||
*[[Eccrine carcinoma]]. | *[[Eccrine carcinoma]]. | ||
==IHC== | |||
Panel: | |||
*CEA +ve (-ve in Bowen's disease, -ve in Toker cells). | |||
*CK7 +ve. (???) | |||
**Toker cells CK7 +ve.<ref name=pmid19601945>{{Cite journal | last1 = Nofech-Mozes | first1 = S. | last2 = Hanna | first2 = W. | title = Toker cells revisited. | journal = Breast J | volume = 15 | issue = 4 | pages = 394-8 | month = | year = | doi = 10.1111/j.1524-4741.2009.00743.x | PMID = 19601945 }}</ref> | |||
*S100 -ve, HMB-45 -ve (both typically +ve in melanoma). | |||
Additional: | |||
*HER2/neu - usually +ve. | |||
*CK5/6 -ve.<ref>RS. May 2010.</ref> | |||
**Usu. +ve in [[squamous cell carcinoma]]. | |||
==See also== | ==See also== | ||