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Difference between revisions of "Dermatopathology"
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→Skin diseases
(→Skin disease and systemic conditions: +images) |
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Bullous diseases, e.g. pemphigus vulgaris, is dealt with in the ''[[bullous disease]]'' article. | Bullous diseases, e.g. pemphigus vulgaris, is dealt with in the ''[[bullous disease]]'' article. | ||
====Common entities==== | |||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
! Entity | |||
! Key histologic feature | |||
! Other features | |||
! Clinical | |||
! Stains/IHC | |||
! DDx | |||
! Other | |||
! Image | |||
|- | |||
| [[Seborrheic keratosis]] (SK) | |||
| horn cysts (intraepidermal collections of keratin) | |||
| hyperkeratosis, brown granular material at the DE junction, sharply demarcated | |||
| stuck on appearance | |||
| none | |||
| [[Fibroepithelial polyp]] | |||
| Leser–Trélat sign = many SKs in malignancy | |||
| [http://commons.wikimedia.org/wiki/File:Seborrheic_keratosis_(1).jpg (WC)] | |||
|- | |||
| [[Dermatofibroma]] | |||
| fibrous bundles esp. at edge of lesion | |||
| "dirty fingers" = acanthosis + basal keratinocyte hyperpigmentation | |||
| +/-trauma Hx | |||
| CD34-, Factor VIIIa+ | |||
| [[DFSP]] | |||
| very common | |||
| [http://www.pacificderm.org/newsflashcpcapril04.html (pacificderm.org)] | |||
|- | |||
| [[Fibroepithelial polyp]] (skin tag) | |||
| on a stalk (epithelium on 3+ sides) | |||
| no horn nests, no hyperkeratosis | |||
| raised lesion | |||
| none | |||
| [[Seborrheic keratosis]] | |||
| very common | |||
| [http://dermatlas.med.jhmi.edu/derm/IndexDisplay.cfm?ImageID=1767547949 (dermatlas.med.jhmi.edu)] | |||
|- <!-- | |||
| Entity | |||
| Key histologic features | |||
| Other features | |||
| Clinical | |||
| Stains/IHC | |||
| DDx | |||
| Other | |||
| Image --> | |||
|} | |||
==Presentations== | ==Presentations== | ||