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===Basic pathologic [[DDx]] of malignancy=== | ===Basic pathologic [[DDx]] of malignancy=== | ||
As a pathologist, this should ''always'' be the first question: | |||
<center> | |||
<!-- | <!-- | ||
DDX OF MALIGNANCY | DDX OF MALIGNANCY - FIRST STEP | ||
--> | |||
{{familytree/start}} | |||
{{familytree | | | |A11| | | | |A11 = Malignancy }} | |||
{{familytree | |,|-|-|^|-|-|.|}} | |||
{{familytree | B11 | | | | B12 |B11=Primary|B12=Metastatic }} | |||
{{familytree/end}} | |||
</center> | |||
Q. Why? <br> | |||
A. The site of the tumour can considerably change the differential diagnosis. <br><br> | |||
After primary vs. metastasis: | |||
<center> | |||
<!-- | |||
DDX OF MALIGNANCY - THE NEXT STEP | |||
--> | --> | ||
{{familytree/start}} | {{familytree/start}} | ||
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{{familytree | B | | C | | D | | E | | F | |G |B=Epithelial<br>(Carcinoma)|C=Mesenchymal<br>(Sarcoma)|D=Germ cell<br>tumour|E=Neuroendocrine<br>carcinoma|F=Lymphoid<br>(Lymphoma)|G=Malignant<br>melanoma}} | {{familytree | B | | C | | D | | E | | F | |G |B=Epithelial<br>(Carcinoma)|C=Mesenchymal<br>(Sarcoma)|D=Germ cell<br>tumour|E=Neuroendocrine<br>carcinoma|F=Lymphoid<br>(Lymphoma)|G=Malignant<br>melanoma}} | ||
{{familytree/end}} | {{familytree/end}} | ||
</center> | |||
Notes: | Notes: |
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