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Difference between revisions of "Ovarian tumours"
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→Thecoma: +images, format
m (→Sex cord stromal tumours: SCTAT) |
(→Thecoma: +images, format) |
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==Thecoma== | ==Thecoma== | ||
* | ===General=== | ||
*Associated with compression & atrophy of ovarian cortex, thought to arise from medulla.<ref name=pmid18164409/> | |||
*Approx. 50% have symptoms related to estrogen secretion.<ref name=pmid16810055/> | *Approx. 50% have symptoms related to estrogen secretion.<ref name=pmid16810055/> | ||
**May also be viralizing. | **May also be viralizing. | ||
=== | ===Microscopic=== | ||
Features:<ref name=pmid16810055/> | Features:<ref name=pmid16810055/> | ||
*Nuclei with oval to spindle morphology. | *Nuclei with oval to spindle morphology. | ||
*Abundant cytoplasm that is pale, vaculolated -- '''key feature'''. | *Abundant cytoplasm that is pale, vaculolated -- '''key feature'''. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Thecoma_low_mag.jpg Thecoma - low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Thecoma_high_mag.jpg Thecoma - high mag. (WC)]. | |||
===IHC=== | |||
*Alpha-inhibin +ve (90%+).<ref name=pmid16810055/> | |||
==Sertoli-Ledydig tumour== | ==Sertoli-Ledydig tumour== | ||