Difference between revisions of "Papillary renal cell carcinoma"

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===Histological subtyping===
===Histological subtyping - historical===
Historically, PaRCC was subtyped:<ref name=Ref_GUP289>{{Ref GUP|289}}</ref><ref>{{Cite journal  | last1 = Delahunt | first1 = B. | last2 = Eble | first2 = JN. | title = Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. | journal = Mod Pathol | volume = 10 | issue = 6 | pages = 537-44 | month = Jun | year = 1997 | doi =  | PMID = 9195569 }}</ref>
Historically, PaRCC was subtyped:<ref name=Ref_GUP289>{{Ref GUP|289}}</ref><ref>{{Cite journal  | last1 = Delahunt | first1 = B. | last2 = Eble | first2 = JN. | title = Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. | journal = Mod Pathol | volume = 10 | issue = 6 | pages = 537-44 | month = Jun | year = 1997 | doi =  | PMID = 9195569 }}</ref>
*''Type 1'' - single layer of cells on basement membrane - '''most important'''.
*''Type 1'' - single layer of cells on basement membrane - '''most important'''.
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The WHO GU Blue Book 5th Ed. recommends against subtyping.
The WHO GU Blue Book 5th Ed. recommends against subtyping.
The defunct ''Type 1'' is papillary renal cell carcinoma.  It is classically associated with a MET gene alteration.
The defunct ''Type 2'' is a mix of other tumour, e.g. ALK-RCC, translocation RCC, FH-deficient RCC.


Another subtype:
Another subtype:
48,987

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