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Difference between revisions of "Residual cancer burden index"
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'''Residual cancer burden index''', abbreviated '''RCB''', is an empirical predictor of outcome in [[breast cancer]] in the [[post-neoadjuvant therapy]] setting.<ref>{{cite journal |authors=Yau C, Osdoit M, van der Noordaa M, Shad S, Wei J, de Croze D, Hamy AS, Laé M, Reyal F, Sonke GS, Steenbruggen TG, van Seijen M, Wesseling J, Martín M, Del Monte-Millán M, López-Tarruella S, Boughey JC, Goetz MP, Hoskin T, Gould R, Valero V, Edge SB, Abraham JE, Bartlett JM, Caldas C, Dunn J, Earl H, Hayward L, Hiller L, Provenzano E, Sammut SJ, Thomas JS, Cameron D, Graham A, Hall P, Mackintosh L, Fan F, Godwin AK, Schwensen K, Sharma P, DeMichele AM, Cole K, Pusztai L, Kim MO, van 't Veer LJ, Esserman LJ, Symmans WF |title=Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients |journal=Lancet Oncol |volume=23 |issue=1 |pages=149–160 |date=January 2022 |pmid=34902335 |doi=10.1016/S1470-2045(21)00589-1 |url=}}</ref> | '''Residual cancer burden index''', abbreviated '''RCB''', is an empirical predictor of outcome in [[breast cancer]] in the [[post-neoadjuvant therapy]] setting.<ref>{{cite journal |authors=Yau C, Osdoit M, van der Noordaa M, Shad S, Wei J, de Croze D, Hamy AS, Laé M, Reyal F, Sonke GS, Steenbruggen TG, van Seijen M, Wesseling J, Martín M, Del Monte-Millán M, López-Tarruella S, Boughey JC, Goetz MP, Hoskin T, Gould R, Valero V, Edge SB, Abraham JE, Bartlett JM, Caldas C, Dunn J, Earl H, Hayward L, Hiller L, Provenzano E, Sammut SJ, Thomas JS, Cameron D, Graham A, Hall P, Mackintosh L, Fan F, Godwin AK, Schwensen K, Sharma P, DeMichele AM, Cole K, Pusztai L, Kim MO, van 't Veer LJ, Esserman LJ, Symmans WF |title=Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients |journal=Lancet Oncol |volume=23 |issue=1 |pages=149–160 |date=January 2022 |pmid=34902335 |doi=10.1016/S1470-2045(21)00589-1 |url=}}</ref> | ||
==Definition== | |||
The [[RCB index]] is defined as: | |||
:<math>RCB = 1.4 \ ( f_{inv} \ d_{prim} )^ {0.17} + \lbrack{ \ 4 \ (1 - 0.75^{LN}) d_{met}} \rbrack ^{0.17}</math> | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
==External links== | |||
*[https://www3.mdanderson.org/app/medcalc/index.cfm?pagename=jsconvert3 Online calculator for RCB index (mdanderson.org)]. | |||
[[Category:Breast pathology]] | [[Category:Breast pathology]] | ||