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Difference between revisions of "Classification of urothelial carcinoma by immunohistochemistry"
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Classification of urothelial carcinoma by immunohistochemistry (view source)
Revision as of 18:45, 15 October 2021
, 18:45, 15 October 2021→General
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==General== | ==General== | ||
*A large meta-analysis showed two markers (CK5/6, GATA3) can subclassify ~90% of urothelial carcinoma into prognostic groups.<ref>{{cite journal |vauthors=Dadhania V, Zhang M, Zhang L, Bondaruk J, Majewski T, Siefker-Radtke A, Guo CC, Dinney C, Cogdell DE, Zhang S, Lee S, Lee JG, Weinstein JN, Baggerly K, McConkey D, Czerniak B |title=Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use |journal=EBioMedicine |volume=12 |issue= |pages=105–117 |date=October 2016 |pmid=27612592 |pmc=5078592 |doi=10.1016/j.ebiom.2016.08.036 |url=}}</ref> | *A large meta-analysis showed two markers (CK5/6, GATA3) can subclassify ~90% of urothelial carcinoma into prognostic groups.<ref>{{cite journal |vauthors=Dadhania V, Zhang M, Zhang L, Bondaruk J, Majewski T, Siefker-Radtke A, Guo CC, Dinney C, Cogdell DE, Zhang S, Lee S, Lee JG, Weinstein JN, Baggerly K, McConkey D, Czerniak B |title=Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use |journal=EBioMedicine |volume=12 |issue= |pages=105–117 |date=October 2016 |pmid=27612592 |pmc=5078592 |doi=10.1016/j.ebiom.2016.08.036 |url=}}</ref> | ||
===A very simple classification of urothelial carcinoma by immunohistochemistry=== | |||
{{familytree/start}} | |||
{{familytree | | | | | | | | | A01 | | | | |A01='''[[Urothelial carcinoma]]'''}} | |||
{{familytree | | | | |,|-|-|-|-|^|-|-|-|-|.|}} | |||
{{familytree | | | | B01 | | | | | | | | B02|B01='''Luminal type'''<br>'''GATA3 +ve'''<br>(CK5/6 -ve)|B02='''Basal type'''<br>'''CK5/6 +ve'''<br>(GATA3 -ve)}} | |||
{{familytree/end}} | |||
===A simple classification of urothelial carcinoma by immunohistochemistry=== | ===A simple classification of urothelial carcinoma by immunohistochemistry=== | ||