110
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Difference between revisions of "Paired box gene 8"
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positive in epithelial component of thymic tumours
m (positive in epithelial component of thymic tumours) |
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*[[Pancreatic neuroendocrine tumour]] ~ 74%.<ref name=pmid20890270>{{Cite journal | last1 = Sangoi | first1 = AR. | last2 = Ohgami | first2 = RS. | last3 = Pai | first3 = RK. | last4 = Beck | first4 = AH. | last5 = McKenney | first5 = JK. | last6 = Pai | first6 = RK. | title = PAX8 expression reliably distinguishes pancreatic well-differentiated neuroendocrine tumors from ileal and pulmonary well-differentiated neuroendocrine tumors and pancreatic acinar cell carcinoma. | journal = Mod Pathol | volume = 24 | issue = 3 | pages = 412-24 | month = Mar | year = 2011 | doi = 10.1038/modpathol.2010.176 | PMID = 20890270 }}</ref> | *[[Pancreatic neuroendocrine tumour]] ~ 74%.<ref name=pmid20890270>{{Cite journal | last1 = Sangoi | first1 = AR. | last2 = Ohgami | first2 = RS. | last3 = Pai | first3 = RK. | last4 = Beck | first4 = AH. | last5 = McKenney | first5 = JK. | last6 = Pai | first6 = RK. | title = PAX8 expression reliably distinguishes pancreatic well-differentiated neuroendocrine tumors from ileal and pulmonary well-differentiated neuroendocrine tumors and pancreatic acinar cell carcinoma. | journal = Mod Pathol | volume = 24 | issue = 3 | pages = 412-24 | month = Mar | year = 2011 | doi = 10.1038/modpathol.2010.176 | PMID = 20890270 }}</ref> | ||
**Can help differentiate from lung NETs. | **Can help differentiate from lung NETs. | ||
*Epithelial component of thymic tumors 77-100% depending on sub-type<ref name=pmid21552115>{{cite journal |vauthors=Laury AR, Perets R, Piao H, Krane JF, Barletta JA, French C, Chirieac LR, Lis R, Loda M, Hornick JL, Drapkin R, Hirsch MS |title=A comprehensive analysis of PAX8 expression in human epithelial tumors |journal=Am. J. Surg. Pathol. |volume=35 |issue=6 |pages=816–26 |date=June 2011 |pmid=21552115 |doi=10.1097/PAS.0b013e318216c112 |url=}}</ref><ref name=pmid21836478>{{cite journal |vauthors=Weissferdt A, Moran CA |title=Pax8 expression in thymic epithelial neoplasms: an immunohistochemical analysis |journal=Am. J. Surg. Pathol. |volume=35 |issue=9 |pages=1305–10 |date=September 2011 |pmid=21836478 |doi=10.1097/PAS.0b013e3182260735 |url=}}</ref> | |||
==Negative staining== | ==Negative staining== | ||