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Difference between revisions of "IDH mutation"
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Seen in:<ref>{{Cite journal | last1 = Capper | first1 = D. | last2 = Reuss | first2 = D. | last3 = Schittenhelm | first3 = J. | last4 = Hartmann | first4 = C. | last5 = Bremer | first5 = J. | last6 = Sahm | first6 = F. | last7 = Harter | first7 = PN. | last8 = Jeibmann | first8 = A. | last9 = von Deimling | first9 = A. | title = Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology. | journal = Acta Neuropathol | volume = 121 | issue = 2 | pages = 241-52 | month = Feb | year = 2011 | doi = 10.1007/s00401-010-0770-2 | PMID = 21069360 }}</ref> | Seen in:<ref>{{Cite journal | last1 = Capper | first1 = D. | last2 = Reuss | first2 = D. | last3 = Schittenhelm | first3 = J. | last4 = Hartmann | first4 = C. | last5 = Bremer | first5 = J. | last6 = Sahm | first6 = F. | last7 = Harter | first7 = PN. | last8 = Jeibmann | first8 = A. | last9 = von Deimling | first9 = A. | title = Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology. | journal = Acta Neuropathol | volume = 121 | issue = 2 | pages = 241-52 | month = Feb | year = 2011 | doi = 10.1007/s00401-010-0770-2 | PMID = 21069360 }}</ref> | ||
*Astrocytoma. | *Astrocytoma. | ||
*Oligodendroglioma (requirement for diagnosis). | *Oligodendroglioma (requirement for diagnosis).<ref>{{Cite journal | last1 = Wesseling | first1 = P. | last2 = Capper | first2 = D. | title = WHO 2016 Classification of gliomas. | journal = Neuropathol Appl Neurobiol | volume = 44 | issue = 2 | pages = 139-150 | month = 02 | year = 2018 | doi = 10.1111/nan.12432 | PMID = 28815663 }}</ref> | ||
*Secondary Glioblastoma. | *Secondary Glioblastoma. | ||
** | **DDx: IDH mutations in PNET are most likely misdiagnosed small cell glioblastomas.<ref>{{Cite journal | last1 = Song | first1 = X. | last2 = Andrew Allen | first2 = R. | last3 = Terence Dunn | first3 = S. | last4 = Fung | first4 = KM. | last5 = Farmer | first5 = P. | last6 = Gandhi | first6 = S. | last7 = Ranjan | first7 = T. | last8 = Demopoulos | first8 = A. | last9 = Symons | first9 = M. | title = Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma. | journal = Int J Clin Exp Pathol | volume = 4 | issue = 7 | pages = 651-60 | month = | year = 2011 | doi = | PMID = 22076165 }}</ref> | ||