Account-creators
1,040
edits
Difference between revisions of "Neuropathology tumours"
Jump to navigation
Jump to search
→Desmoplastic infantile astrocytoma / Desmoplastic infantile ganglioglioma: typo and update
Jensflorian (talk | contribs) (→Molecular=: fix) |
Jensflorian (talk | contribs) (→Desmoplastic infantile astrocytoma / Desmoplastic infantile ganglioglioma: typo and update) |
||
| Line 374: | Line 374: | ||
**GFAP+. | **GFAP+. | ||
**MIB-1 usu. 1%. | **MIB-1 usu. 1%. | ||
* | * Frequent BRAF V600E or V600D mutations.<ref>{{Cite journal | last1 = Wang | first1 = AC. | last2 = Jones | first2 = DTW. | last3 = Abecassis | first3 = IJ. | last4 = Cole | first4 = BL. | last5 = Leary | first5 = SES. | last6 = Lockwood | first6 = CM. | last7 = Chavez | first7 = L. | last8 = Capper | first8 = D. | last9 = Korshunov | first9 = A. | title = Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) are Distinct Entities with Frequent BRAFV600 Mutations. | journal = Mol Cancer Res | volume = | issue = | pages = | month = Jul | year = 2018 | doi = 10.1158/1541-7786.MCR-17-0507 | PMID = 30006355 }}</ref> | ||
*Single case with BRAF indel or BRAF fusion. | |||
<gallery> | <gallery> | ||
File:DIG-histology.jpg | Histopathology of DIG (HE stain) | File:DIG-histology.jpg | Histopathology of DIG (HE stain) | ||