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Difference between revisions of "Mucinous cystadenoma of the ovary"
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Mucinous cystadenoma of the ovary (view source)
Revision as of 16:36, 1 March 2018
, 16:36, 1 March 2018no edit summary
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| IHC = | | IHC = | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = +/-[[KRAS mutation]] | ||
| IF = | | IF = | ||
| Gross = multiloculated cystic lesion, thin cyst walls/no solid areas | | Gross = multiloculated cystic lesion, thin cyst walls/no solid areas | ||
| Line 55: | Line 55: | ||
Note: | Note: | ||
*A borderline component may be present but | *A borderline component may be present but ''must be <10%'' of the tumour.<ref name=Ref_GP>{{Ref GP|416}}</ref> | ||
**Lesions with <10% borderline component are known as ''mucinous cystadenoma of the ovary with focal proliferation'' or ''mucinous cystadenoma of the ovary with focal atypia''. | **Lesions with <10% borderline component are known as ''mucinous cystadenoma of the ovary with focal proliferation'' or ''mucinous cystadenoma of the ovary with focal atypia''. | ||
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Image: Ovarian mucinous cystadenoma - a3- very high mag.jpg | OMC - very high mag. | Image: Ovarian mucinous cystadenoma - a3- very high mag.jpg | OMC - very high mag. | ||
</gallery> | </gallery> | ||
==Molecular== | |||
*[[KRAS mutation]]s common ~ 56% of mucinous cystadenomas in one series.<ref name=pmid9118042>{{Cite journal | last1 = Cuatrecasas | first1 = M. | last2 = Villanueva | first2 = A. | last3 = Matias-Guiu | first3 = X. | last4 = Prat | first4 = J. | title = K-ras mutations in mucinous ovarian tumors: a clinicopathologic and molecular study of 95 cases. | journal = Cancer | volume = 79 | issue = 8 | pages = 1581-6 | month = Apr | year = 1997 | doi = | PMID = 9118042 }}</ref> | |||
==Sign out== | ==Sign out== | ||
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Left Ovarian Cyst, Excision: | Left Ovarian Cyst, Excision: | ||
- Mucinous cystadenoma. | - Mucinous cystadenoma. | ||
</pre> | |||
===Mucinous cystadenoma with focal proliferation=== | |||
<pre> | |||
Left Ovarian Cyst, Excision: | |||
- Mucinous cystadenoma with focal proliferation, see comment. | |||
Comment: | |||
The proliferative component is less than 10% of the lesion. | |||
</pre> | </pre> | ||
==See also== | ==See also== | ||
*[[Ovarian tumours]]. | *[[Ovarian tumours]]. | ||
*[[Mucinous ovarian tumours]]. | |||
*[[Mucinous cystadenoma]]. | *[[Mucinous cystadenoma]]. | ||
*[[Mucinous cystadenoma of the appendix]]. | *[[Mucinous cystadenoma of the appendix]]. | ||