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Difference between revisions of "Lung tumours"
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→IHC: wikify
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===Small cell carcinoma=== | ===Small cell carcinoma=== | ||
*TTF-1 +ve. | *[[TTF-1]] +ve. | ||
*[[CD56]] +ve - sensitive.<ref name=pmid16862075>{{cite journal |author=Hiroshima K, Iyoda A, Shida T, ''et al'' |title=Distinction of pulmonary large cell neuroendocrine carcinoma from small cell lung carcinoma: a morphological, immunohistochemical, and molecular analysis |journal=Mod. Pathol. |volume=19 |issue=10 |pages=1358-68 |year=2006 |month=October |pmid=16862075 |doi=10.1038/modpathol.3800659 |url=}}</ref> | *[[CD56]] +ve - sensitive.<ref name=pmid16862075>{{cite journal |author=Hiroshima K, Iyoda A, Shida T, ''et al'' |title=Distinction of pulmonary large cell neuroendocrine carcinoma from small cell lung carcinoma: a morphological, immunohistochemical, and molecular analysis |journal=Mod. Pathol. |volume=19 |issue=10 |pages=1358-68 |year=2006 |month=October |pmid=16862075 |doi=10.1038/modpathol.3800659 |url=}}</ref> | ||
*[[CK7]] -ve, [[CK20]] -ve. | *[[CK7]] -ve, [[CK20]] -ve. | ||
| Line 95: | Line 95: | ||
===Squamous cell carcinoma=== | ===Squamous cell carcinoma=== | ||
*CK7 -ve, CK20 -ve. | *[[CK7]] -ve, CK20 -ve. | ||
*HMWK +ve. | *HMWK +ve. | ||
*Usually TTF-1 -ve.<ref>{{cite journal |author=Al-Zahrani IH |title=The value of immunohistochemical expression of TTF-1, CK7 and CK20 in the diagnosis of primary and secondary lung carcinomas |journal=Saudi Med J |volume=29 |issue=7 |pages=957-61 |year=2008 |month=July |pmid=18626520 |doi= |url=}}</ref> | *Usually TTF-1 -ve.<ref>{{cite journal |author=Al-Zahrani IH |title=The value of immunohistochemical expression of TTF-1, CK7 and CK20 in the diagnosis of primary and secondary lung carcinomas |journal=Saudi Med J |volume=29 |issue=7 |pages=957-61 |year=2008 |month=July |pmid=18626520 |doi= |url=}}</ref> | ||
*p40 +ve. | *[[p40]] +ve. | ||
===Primary vs. secondary=== | ===Primary vs. secondary=== | ||