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Comment 1: There is a cluster of tumour cells without adjacent lymphoid tissue. This is thought to represent extranodal extension; however, it may represent a tumour deposit. <br> | Comment 1: There is a cluster of tumour cells without adjacent lymphoid tissue. This is thought to represent extranodal extension; however, it may represent a tumour deposit. <br> | ||
Comment 2: The lymph node counts in part A, B and C are estimates, as the lymph nodes were matted. | Comment 2: The lymph node counts in part A, B and C are estimates, as the lymph nodes were matted. | ||
== Lymphocytic thyroiditis == | |||
===Microscopic=== | |||
A. The sections show thyroid gland with extensive fibrosis and lymphoid follicles, with well-developed germinal centres and tingible-body macrophages. Follicular cells show focal enlargement and nucleoli in association with a lymphoplasmic infiltrate. There is no nuclear clearing, no nuclear grooves and no nuclear pseudoinclusions. There is no evidence of malignancy. | |||
One focus of benign parathyroid tissue is present. There are three benign lymph nodes with sinus histiocytosis. The sinus histiocytes have round nuclei less than two times the size of a mature lymphocyte. | |||
===Final diagnosis=== | |||
A. Hemithyroid, right, hemithyroidectomy - <br> | |||
i) Lymphocytic thyroiditis <br> | |||
ii) Parathyroid tissue present <br> | |||
iii) Three benign lymph nodes with sinus histiocytosis. |
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