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Difference between revisions of "Hepatitis C"
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Hepatitis C virus. Metavir Activity Index 1 (PMN 0 LN 1). | Hepatitis C virus. Metavir Activity Index 1 (PMN 0 LN 1). | ||
Preserved architecture shows small, inflamed triads [red arrows] and foci of spotty necrosis [blue arrows] (Row 1 Left 40X). Trichrome shows periportal fibrosis [blue arrow] and central venous sclerosis [green arrow] (Row 1 Right 100X). A higher power view of an inflamed triad with interface hepatitis, but a smooth outline, suggesting no piecemeal necrosis (Row 2 Left 200X). A focus of spotty necrosis near an unafflicted triad below it (Row 2 Right 200X). Reticulin shows collapse [arrows] extending from/near portal triad without piecemeal necrosis (Row 3 Left 200X). Reticulin shows collapse [arrows] extending from/near central vein (Row 3 Right 200X). | Preserved architecture shows small, inflamed triads [red arrows] and foci of spotty necrosis [blue arrows] (Row 1 Left 40X). Trichrome shows periportal fibrosis [blue arrow] and central venous sclerosis [green arrow] (Row 1 Right 100X). A higher power view of an inflamed triad with interface hepatitis, but a smooth outline, suggesting no piecemeal necrosis (Row 2 Left 200X). A focus of spotty necrosis near an unafflicted triad below it (Row 2 Right 200X). Reticulin shows collapse [arrows] extending from/near portal triad without piecemeal necrosis (Row 3 Left 200X). Reticulin shows collapse [arrows] extending from/near central vein (Row 3 Right 200X). | ||
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[[File:1 HCV 11 680x512px.tif]] | |||
[[File:2 HCV 11 680x512px.tif]] | |||
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[[File:3 HCV 11 680x512px.tif]] | |||
[[File:4 HCV 11 680x512px.tif]] | |||
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[[File:5 HCV 11 680x512px.tif]] | |||
[[File:6 HCV 11 680x512px.tif]] | |||
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Hepatitis C virus. Metavir activity index 1 (PMN 1 LN 1). Triads show inflammation with extension to portal border (interface hepatitis) (Row 1 Left 40X). Lymphocyte aggregates denote spotty necrosis (Row 1 Right 200X). Reticulin shows focal piecemeal necrosis [arrow] (Row 2 Left 200X). Trichrome shows periportal fibrous extension [arrows] (Row 2 Right 200X). Trichrome shows sclerosis of central vein (Row 3 Left 200X). PAS D can be useful when steatosis frustrates rosette identification; hepatocyte rosettes [arrows] have red edges (Row 3 Right 400X). | |||
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