Difference between revisions of "Steatohepatitis"

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===Brunt grading system===
====Brunt grading system====
Brunt's 1999 paper proposed a system:<ref name=pmid10484010>{{Cite journal  | last1 = Brunt | first1 = EM. | last2 = Janney | first2 = CG. | last3 = Di Bisceglie | first3 = AM. | last4 = Neuschwander-Tetri | first4 = BA. | last5 = Bacon | first5 = BR. | title = Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. | journal = Am J Gastroenterol | volume = 94 | issue = 9 | pages = 2467-74 | month = Sep | year = 1999 | doi = 10.1111/j.1572-0241.1999.01377.x | PMID = 10484010 }}</ref>
Brunt's 1999 paper proposed a system:<ref name=pmid10484010>{{Cite journal  | last1 = Brunt | first1 = EM. | last2 = Janney | first2 = CG. | last3 = Di Bisceglie | first3 = AM. | last4 = Neuschwander-Tetri | first4 = BA. | last5 = Bacon | first5 = BR. | title = Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. | journal = Am J Gastroenterol | volume = 94 | issue = 9 | pages = 2467-74 | month = Sep | year = 1999 | doi = 10.1111/j.1572-0241.1999.01377.x | PMID = 10484010 }}</ref>
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===Staging steatohepatitis===
{| class="wikitable sortable"
! Stage
! Fibrosis
! Notes
|-
| 0
| none
| -
|-
| 1
| zone 3 perisinusoidal
| may be focal or extensive
|-
| 2
| perisinusoidal and periportal
| no bridging
|-
| 3
| bridging fibrosis
| no nodule formation
|-
| 4
| nodule formation
|
|}


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