Difference between revisions of "Parathyroid glands"

Parathyroid glands (view source)

1,043 bytes removed , 03:56, 7 June 2016

48,830

edits

@@ Line 174: / Line 174: @@
 ==Parathyroid carcinoma==
-===General===
+{{Main|Parathyroid carcinoma}}
-*Extremely rare.
-===Microscopic===
-Features:<ref>{{Ref PBoD8|1128}}</ref>
-*Histologically normal parathyroid cells.
-**Cytologic features '''not''' reliable for diagnosis.
-*Fibrous capsule.
-*Invasion of surrounding tissue - '''key feature'''.
-*+/-[[Metastasis]] - '''diagnostic feature'''.
-Note:
-*Diagnosis of ''parathyroid carcinoma'' is like that of ''malignant [[pheochromocytoma]]'' - cytology useless, tissue invasion and metastases are the key features.
-Image:
-*[http://emedicine.medscape.com/article/280908-overview Parathyroid carcinoma (medscape.com)].
-===IHC===
-*Ki-67 >6% of cells positive - supports diagnosis.<ref name=pmid7860042>{{Cite journal  | last1 = Abbona | first1 = GC. | last2 = Papotti | first2 = M. | last3 = Gasparri | first3 = G. | last4 = Bussolati | first4 = G. | title = Proliferative activity in parathyroid tumors as detected by Ki-67 immunostaining. | journal = Hum Pathol | volume = 26 | issue = 2 | pages = 135-8 | month = Feb | year = 1995 | doi =  | PMID = 7860042 }}</ref>
-**Parathyroid adenomas and hyperplasias ~ 3%.
 =See also=