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Difference between revisions of "Giardiasis"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Giardia_small_bowel_--_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Giardiasis. [[H&E stain]]. | | Caption = Giardiasis. [[H&E stain]]. | ||
| Line 19: | Line 19: | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = | ||
| Signs = diarrhea | | Signs = diarrhea x5 days, foul smelling feces, flatulence | ||
| Symptoms = | | Symptoms = fatigue, abdominal cramps, nausea | ||
| Prevalence = uncommon | | Prevalence = uncommon | ||
| Bloodwork = | | Bloodwork = | ||
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==General== | ==General== | ||
Clinical features:<ref name=pmid1994703>{{Cite journal | last1 = Hopkins | first1 = RS. | last2 = Juranek | first2 = DD. | title = Acute giardiasis: an improved clinical case definition for epidemiologic studies. | journal = Am J Epidemiol | volume = 133 | issue = 4 | pages = 402-7 | month = Feb | year = 1991 | doi = | PMID = 1994703 }}</ref> | Clinical features - usually two or more of the following:<ref name=pmid1994703>{{Cite journal | last1 = Hopkins | first1 = RS. | last2 = Juranek | first2 = DD. | title = Acute giardiasis: an improved clinical case definition for epidemiologic studies. | journal = Am J Epidemiol | volume = 133 | issue = 4 | pages = 402-7 | month = Feb | year = 1991 | doi = | PMID = 1994703 }}</ref> | ||
*Diarrhea - x5 days. | *Diarrhea - x5 days. | ||
*Flatulence. | *Flatulence. | ||
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*Uncommon. | *Uncommon. | ||
Etiology: | |||
*Flagellate protozoan ''Giardia lamblia''. | |||
Treatment | |||
*Antibiotics, e.g. metronidazole (Flagyl). | |||
==Gross== | ==Gross== | ||
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Features: | Features: | ||
*+/-Loss of villi. | *+/-Loss of villi. | ||
*Intraepithelial lymphocytes. | *[[Intraepithelial lymphocytes]]. | ||
**+Other inflammatory cells, especially PMNs, close to the luminal surface. | **+Other inflammatory cells, especially [[PMNs]], close to the luminal surface. | ||
*Flagellate protozoa -- '''diagnostic feature'''. | *Flagellate protozoa -- '''diagnostic feature'''. | ||
**Organisms often at site of bad inflammation. | **Organisms often at site of bad inflammation. | ||
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===Images=== | ===Images=== | ||
====Case 1==== | |||
<gallery> | <gallery> | ||
Image:Giardiasis_duodenum_high.jpg | Giardiasis - high mag. (WC) | Image:Giardiasis_duodenum_high.jpg | Giardiasis - high mag. (WC) | ||
Image:Giardiasis_duodenum_low.jpg | Giardiasis - low mag. (WC) | Image:Giardiasis_duodenum_low.jpg | Giardiasis - low mag. (WC) | ||
</gallery> | </gallery> | ||
www | ====Case 2==== | ||
*[http://path.upmc.edu/cases/case278.html Giardiasis - several | <gallery> | ||
Giardia small bowel -- low mag.jpg | Giardia - low mag. | |||
Giardia small bowel -- intermed mag.jpg | Giardia - intermed. mag. | |||
Giardia small bowel -- high mag.jpg | Giardia - high mag. | |||
Giardia small bowel - alt -- high mag.jpg | Giardia - high mag. | |||
Giardia small bowel -- very high mag.jpg | Giardia - very high mag. | |||
</gallery> | |||
====www==== | |||
*[http://path.upmc.edu/cases/case278.html Giardiasis - several images (upmc.edu)]. | |||
==Stains== | ==Stains== | ||