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'''Multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis''', also '''multifocal micronodular pneumocyte hyperplasia in tuberous sclerosis''', is the presence of rare hamartomatous lesions in the [[lung]] seen in [[tuberous sclerosis]].<ref name=pmid18234663 >{{Cite journal | last1 = Nagar | first1 = AM. | last2 = Teh | first2 = HS. | last3 = Khoo | first3 = RN. | last4 = Morani | first4 = AC. | last5 = Vrishni | first5 = K. | last6 = Raghuram | first6 = J. | title = Multifocal pneumocyte hyperplasia in tuberous sclerosis. | journal = Thorax | volume = 63 | issue = 2 | pages = 186 | month = Feb | year = 2008 | doi = 10.1136/thx.2006.076604 | PMID = 18234663 }}</ref> | '''Multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis''', also '''multifocal micronodular pneumocyte hyperplasia in tuberous sclerosis''', is the presence of rare hamartomatous lesions in the [[lung]] seen in [[tuberous sclerosis]].<ref name=pmid18234663 >{{Cite journal | last1 = Nagar | first1 = AM. | last2 = Teh | first2 = HS. | last3 = Khoo | first3 = RN. | last4 = Morani | first4 = AC. | last5 = Vrishni | first5 = K. | last6 = Raghuram | first6 = J. | title = Multifocal pneumocyte hyperplasia in tuberous sclerosis. | journal = Thorax | volume = 63 | issue = 2 | pages = 186 | month = Feb | year = 2008 | doi = 10.1136/thx.2006.076604 | PMID = 18234663 }}</ref> | ||
==General== | |||
*Rare. | |||
==Microscopic== | |||
Features: | |||
*Macrophages within the air spaces. | |||
*Enlarged alveolar lining cells with: | |||
**Hobnail morphology - free (luminal) surface area > attached/basal surface area. | |||
**Round or oval nuclei. | |||
DDx: | |||
*[[Atypical adenomatous hyperplasia of the lung]] - usu. do not have macrophages within the air spaces. | |||
===Images=== | |||
<gallery> | |||
Image: Multifocal micronodular pneumocyte hyperplasia - tuberous sclerosis - a3 -- intermed mag.jpg | MMPH - intermed. mag. | |||
Image: Multifocal micronodular pneumocyte hyperplasia - tuberous sclerosis - a3 -- high mag.jpg | MMPH - high mag. | |||
</gallery> | |||
==See also== | ==See also== |
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