48,688
edits
(→Chorangioma: +ref.) |
(→Chorangioma: more) |
||
Line 676: | Line 676: | ||
Epidemiology: | Epidemiology: | ||
*Often benign/insignificant; large lesions (> | *Often benign/insignificant; large lesions (>4 cm<ref name=pmid20594143>{{cite journal |author=Amer HZ, Heller DS |title=Chorangioma and related vascular lesions of the placenta--a review |journal=Fetal Pediatr Pathol |volume=29 |issue=4 |pages=199–206 |year=2010 |pmid=20594143 |doi=10.3109/15513815.2010.487009 |url=}}</ref> or >5 cm<ref name=pmid21234259>{{cite journal |author=Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K |title=Chorangioma placentae |journal=Rare Tumors |volume=2 |issue=4 |pages=e67 |year=2010 |pmid=21234259 |pmc=3019602 |doi=10.4081/rt.2010.e67 |url=}}</ref>) or multiple lesions are significant. | ||
*May be association with: | *May be association with: | ||
**Fetal maternal haemorrhage. | **Fetal maternal haemorrhage. | ||
**Hydrops. | **Hydrops. | ||
**[[IUGR]]. | **[[IUGR]]. | ||
*Incidence: ~1 in 100 placentas.<ref name=pmid20594143/> | |||
===Gross=== | ===Gross=== | ||
Line 687: | Line 688: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=pmid20594143/> | ||
*Mass of capillaries. | *Mass of capillaries - '''key feature'''. | ||
*+/-High cellularity. | |||
*+/-Degenerative changes. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Chorangioma_-_intermed_mag.jpg Chorangioma (WC)]. | *[http://commons.wikimedia.org/wiki/File:Chorangioma_-_intermed_mag.jpg Chorangioma - intermed. mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Chorangioma_-_low_mag.jpg Chorangioma - low mag. (WC)]. | |||
Notes: | |||
*Must be differentiated from chorangiomatosis (assoc. with preeclampsia & IUGR) and chorangiosis (assoc. with maternal [[diabetes mellitus]]).<ref name=pmid20594143/> | |||
==Chorangiosis== | ==Chorangiosis== |
edits