Difference between revisions of "Florid epithelial hyperplasia"

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Image: Proliferative fibrocystic changes -- very high mag.jpg|PFCC - very high mag.
Image: Proliferative fibrocystic changes -- very high mag.jpg|PFCC - very high mag.
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==IHC==
Features:<ref name=pmid19675450>{{Cite journal  | last1 = Grin | first1 = A. | last2 = O'Malley | first2 = FP. | last3 = Mulligan | first3 = AM. | title = Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy. | journal = Am J Surg Pathol | volume = 33 | issue = 11 | pages = 1615-23 | month = Nov | year = 2009 | doi = 10.1097/PAS.0b013e3181aec446 | PMID = 19675450 }}</ref>
*ER "low".
*CK5 "high".
Where:
*ER "high" = diffuse strong staining in >90% of cells.
*CK5 "high" = mosaic pattern of staining in >20% of cells
*CK5 "low" = absent or staining in <20% of cells.
Note:
*ADH/DCIS:
**ER "high"
**CK5 "low".


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