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Difference between revisions of "Radical prostatectomy"
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**The prostate should be weighted after trimming the seminal vesicles. | **The prostate should be weighted after trimming the seminal vesicles. | ||
**The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin). | **The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin). | ||
*Lymph nodes | *Lymph nodes:<ref name=pmid20818343>{{Cite journal | last1 = Berney | first1 = DM. | last2 = Wheeler | first2 = TM. | last3 = Grignon | first3 = DJ. | last4 = Epstein | first4 = JI. | last5 = Griffiths | first5 = DF. | last6 = Humphrey | first6 = PA. | last7 = van der Kwast | first7 = T. | last8 = Montironi | first8 = R. | last9 = Delahunt | first9 = B. | title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. | journal = Mod Pathol | volume = 24 | issue = 1 | pages = 39-47 | month = Jan | year = 2011 | doi = 10.1038/modpathol.2010.160 | PMID = 20818343 }}</ref> | ||
**All lymph nodes should be submitted. | **All lymph nodes should be submitted. | ||
***Metastases are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal | last1 = Epstein | first1 = JI. | last2 = Oesterling | first2 = JE. | last3 = Eggleston | first3 = JC. | last4 = Walsh | first4 = PC. | title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. | journal = J Urol | volume = 136 | issue = 6 | pages = 1234-7 | month = Dec | year = 1986 | doi = | PMID = 3773097 }}</ref> thus, it makes sense to submit all tissue.<ref>{{Cite journal | last1 = Sung | first1 = MT. | last2 = davidson | first2 = DD. | last3 = Montironi | first3 = R. | last4 = Lopez-Beltran | first4 = A. | last5 = Cheng | first4 = L. | title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. | journal = Current Diagnostic Pathology | volume = 13 | issue = | pages = 490-498 | month = | year = 2007 | doi = | PMID = | URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref> | ***Metastases are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal | last1 = Epstein | first1 = JI. | last2 = Oesterling | first2 = JE. | last3 = Eggleston | first3 = JC. | last4 = Walsh | first4 = PC. | title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. | journal = J Urol | volume = 136 | issue = 6 | pages = 1234-7 | month = Dec | year = 1986 | doi = | PMID = 3773097 }}</ref> thus, it makes sense to submit all tissue.<ref>{{Cite journal | last1 = Sung | first1 = MT. | last2 = davidson | first2 = DD. | last3 = Montironi | first3 = R. | last4 = Lopez-Beltran | first4 = A. | last5 = Cheng | first4 = L. | title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. | journal = Current Diagnostic Pathology | volume = 13 | issue = | pages = 490-498 | month = | year = 2007 | doi = | PMID = | URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref> | ||
**The base of the SV | *Seminal vesicles (SV):<ref name=pmid20818343/> | ||
**The base of the SV (adjacent to SV-prostate junction) must be submitted. | |||
***Only ''extraprostatic seminal vesicle involvement'' is considered ''seminal vesicle invasion''. | |||
***SV does ''not'' have to be [[submitted in total]]. | ***SV does ''not'' have to be [[submitted in total]]. | ||