Difference between revisions of "Pleural invasion"

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21 bytes added ,  03:38, 23 October 2015
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!Tumour stage ([[TNM staging]])
!Tumour stage ([[TNM staging]])
|-
|-
|PL0  
|PL0  
|tumour confined to lung, not through elastic layer
|tumour confined to lung, not through elastic layer
|T(any)
|T(any)
|-
|-
|PL1  
|PL1  
|tumour beyond (external) elastic layer of the visercal pleura, not at pleural surface
|tumour beyond (external) elastic layer of the visercal pleura, not at pleural surface
|at least T2
|at least T2
|-
|-
|PL2  
|PL2  
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|}
|}


Note:
Notes:
*The interface between PL0 and PL1 is the most challenging.  Use of an elastic stain is recommend when there is uncertainty.<ref name=pmid23020722/>
*The interface between PL0 and PL1 is the most challenging.  Use of an elastic stain is recommend when there is uncertainty.<ref name=pmid23020722/>
*The up-staging of small tumours is not completely without controversy; there is data for lung adenocarcinomas less than 2 cm that suggests VPI is not an outcome predictor.<ref name=pmid23807749>{{Cite journal  | last1 = Nitadori | first1 = J. | last2 = Colovos | first2 = C. | last3 = Kadota | first3 = K. | last4 = Sima | first4 = CS. | last5 = Sarkaria | first5 = IS. | last6 = Rizk | first6 = NP. | last7 = Rusch | first7 = VW. | last8 = Travis | first8 = WD. | last9 = Adusumilli | first9 = PS. | title = Visceral pleural invasion does not affect recurrence or overall survival among patients with lung adenocarcinoma ≤ 2 cm: a proposal to reclassify T1 lung adenocarcinoma. | journal = Chest | volume = 144 | issue = 5 | pages = 1622-31 | month = Nov | year = 2013 | doi = 10.1378/chest.13-0394 | PMID = 23807749 }}</ref>
*The up-staging of small tumours is not completely without controversy; there is data for lung adenocarcinomas less than 2 cm that suggests VPI is not an outcome predictor.<ref name=pmid23807749>{{Cite journal  | last1 = Nitadori | first1 = J. | last2 = Colovos | first2 = C. | last3 = Kadota | first3 = K. | last4 = Sima | first4 = CS. | last5 = Sarkaria | first5 = IS. | last6 = Rizk | first6 = NP. | last7 = Rusch | first7 = VW. | last8 = Travis | first8 = WD. | last9 = Adusumilli | first9 = PS. | title = Visceral pleural invasion does not affect recurrence or overall survival among patients with lung adenocarcinoma ≤ 2 cm: a proposal to reclassify T1 lung adenocarcinoma. | journal = Chest | volume = 144 | issue = 5 | pages = 1622-31 | month = Nov | year = 2013 | doi = 10.1378/chest.13-0394 | PMID = 23807749 }}</ref>


==Gross==
==Gross==
48,830

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