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Difference between revisions of "Case 96"
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→Diagnosis
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{{hidden|Diagnosis|<center>[[Hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]]</center><br> | {{hidden|Diagnosis|<center>[[Hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]]</center><br> | ||
Comment:<br> | Comment:<br> | ||
The hyalinized papillae and prominent nucleoli with halos are characteristic. These | The hyalinized papillae and prominent nucleoli with halos are characteristic. These tumours often have a mixture of morphologic patterns as seen here (tubulocystic, papillary), and tend to have an aggressive behaviour. The definitive stain is FH (fumarate hydratase); it is lost in HLRCC. The IHC pattern doesn't fit [[papillary RCC]]; HLRCC is typically CK7 negative, CK20 negative and CD10 negative. | ||
}} | }} | ||
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===Other cases=== | ===Other cases=== | ||
{{Cases navigation}} | {{Cases navigation}} | ||