Difference between revisions of "Case 116"

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[[Image: Leiomyoma with changes secondary to tranexamic acid treatment low magnification.jpg |500px|link=|center|]]
[[Image: Leiomyoma with changes secondary to tranexamic acid treatment low magnification.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>
<center>Low magnification. [[H&E stain]].</center>
{{hidden|Intermediate magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}


{{hidden|High magnification|[[Image: Leiomyoma with changes secondary to tranexamic acid treatment high magnification.jpg |500px|link=|center|]]
{{hidden|High magnification|[[Image: Leiomyoma with changes secondary to tranexamic acid treatment high magnification.jpg |500px|link=|center|]]
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===Differential diagnosis===
===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[Smooth muscle tumour of uncertain malignant potential]] (STUMP), [[uterine leiomyosarcoma]] </center>}}
{{hidden|Differential diagnosis|<center>[[Smooth muscle tumour of uncertain malignant potential]] (STUMP), [[uterine leiomyosarcoma]]</center>}}


===Additional tests===
===Additional tests===
====More history====
====More history====
{{hidden|More history|<center>Patient had received lysteda for control of bleeding </center>}}
{{hidden|More history|<center>Patient had received lysteda for control of bleeding.</center>}}


====Ask a colleague====
====Ask a colleague====
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===Diagnosis===
===Diagnosis===
{{hidden|Diagnosis|<center>[[uterine leiomyoma|LEIOMYOMA]] WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION</center><br>  
{{hidden|Diagnosis|<center>[[uterine leiomyoma|LEIOMYOMA]] WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION</center><br>  
This smooth muscle tumor depicts no atypia.  When in this situation it is prudent to request detailed [[clinical history]].  Clinicians often do not inform of all agents given to patients to control uterine bleeding.   <ref>{{Cite journal  | last1 = Ip | first1 = PP. | last2 = Lam | first2 = KW. | last3 = Cheung | first3 = CL. | last4 = Yeung | first4 = MC. | last5 = Pun | first5 = TC. | last6 = Chan | first6 = QK. | last7 = Cheung | first7 = AN. | title = Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. | journal = Am J Surg Pathol | volume = 31 | issue = 8 | pages = 1215-24 | month = Aug | year = 2007 | doi = 10.1097/PAS.0b013e318032125e | PMID = 17667546 }}</ref>
This smooth muscle tumor depicts no atypia.  When in this situation it is prudent to request detailed [[clinical history]].  Clinicians often do not inform of all agents given to patients to control uterine bleeding.<ref name=pmid17667546>{{Cite journal  | last1 = Ip | first1 = PP. | last2 = Lam | first2 = KW. | last3 = Cheung | first3 = CL. | last4 = Yeung | first4 = MC. | last5 = Pun | first5 = TC. | last6 = Chan | first6 = QK. | last7 = Cheung | first7 = AN. | title = Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. | journal = Am J Surg Pathol | volume = 31 | issue = 8 | pages = 1215-24 | month = Aug | year = 2007 | doi = 10.1097/PAS.0b013e318032125e | PMID = 17667546 }}</ref>
===References===
===References===
{{Reflist|1}}
{{Reflist|1}}
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[[Category:Cases]]
[[Category:Cases]]


<!-- SELECT A CATEGORY
[[Category:Cases in gynecologic pathology]]
[[Category:Cases in gynecologic pathology]]
-->
[[Category:Cases in gynecologic pathology - fellow and expert]]


[[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->
[[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->
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