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Difference between revisions of "Autoimmune hepatitis"
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→Microscopic
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**Lots of plasma cells should prompt consideration of AIH. | **Lots of plasma cells should prompt consideration of AIH. | ||
*Atypical Autoimmune hepatitis may have zone III involvment (lymphoplasmacytic infiltrate)<ref name=pmid19452572>Non-classical phenotypes of autoimmune hepatitis and advances in diagnosis and treatment. Czaja AJ, Bayraktar Y. World J Gastroenterol. 2009 May 21;15(19):2314-28. Review. PMID 19452572.</ref> and a normal IgG.<ref>FW. 21 September 2009.</ref> | *Atypical Autoimmune hepatitis may have zone III involvment (lymphoplasmacytic infiltrate)<ref name=pmid19452572>Non-classical phenotypes of autoimmune hepatitis and advances in diagnosis and treatment. Czaja AJ, Bayraktar Y. World J Gastroenterol. 2009 May 21;15(19):2314-28. Review. PMID 19452572.</ref> and a normal IgG.<ref>FW. 21 September 2009.</ref> | ||
DDx: | |||
*[[Viral hepatitis]] - should have plasma cells. | |||
*[[Drug-induced liver injury]] - milder changes than AIH, portal [[neutrophil]]s and [[cholestasis]].<ref>{{Cite journal | last1 = Suzuki | first1 = A. | last2 = Brunt | first2 = EM. | last3 = Kleiner | first3 = DE. | last4 = Miquel | first4 = R. | last5 = Smyrk | first5 = TC. | last6 = Andrade | first6 = RJ. | last7 = Lucena | first7 = MI. | last8 = Castiella | first8 = A. | last9 = Lindor | first9 = K. | title = The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury. | journal = Hepatology | volume = 54 | issue = 3 | pages = 931-9 | month = Sep | year = 2011 | doi = 10.1002/hep.24481 | PMID = 21674554 }}</ref> | |||
===Images=== | ===Images=== | ||