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Difference between revisions of "Liver pathology"
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**Bile duct - round, has a lumen - approximately the size of the artery. | **Bile duct - round, has a lumen - approximately the size of the artery. | ||
***Cuboidal epithelium, central nucleus, lightly basophilic cytoplasm. | ***Cuboidal epithelium, central nucleus, lightly basophilic cytoplasm. | ||
***IHC: CK7 +ve. | ***IHC: [[CK7]] +ve. | ||
***Irregular bile ducts without a lumen are called ''bile ductules''; ''ductule'' implies a pathologic process. | ***Irregular bile ducts without a lumen are called ''bile ductules''; ''ductule'' implies a pathologic process. | ||
*Lobule - hepatocytes. | *Lobule - hepatocytes. | ||
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Common IHC:<ref name=ap27may2009>Pollet, A. 27 May 2009.</ref> | Common IHC:<ref name=ap27may2009>Pollet, A. 27 May 2009.</ref> | ||
*CK7 - bile ducts, and bile ductules +ve. | *[[CK7]] - bile ducts, and bile ductules +ve. | ||
*CD34 - should be -ve in normal liver. | *CD34 - should be -ve in normal liver. | ||
**CD34 marks endothelial cells - these are not present in a healthy liver lobule. | **CD34 marks endothelial cells - these are not present in a healthy liver lobule. | ||