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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Prostatic stromal tumor of uncertain malignant potential - 1 WBAL.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Prostatic stromal tumour of uncertain malignant potential. (WC/George Netto) | ||
| Synonyms = | | Synonyms = prostatic stromal proliferation of uncertain malignant potential | ||
| Micro = increased stromal cellularity, +/-nuclear atypia, +/-benign glands, lack small round blood vessels, no necrosis, no or minimal mitotic activity | | Micro = increased stromal cellularity, +/-nuclear atypia, +/-benign glands, lack small round blood vessels, no necrosis, no or minimal mitotic activity | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[prostatic stromal sarcoma]], stromal nodule in [[benign prostatic hyperplasia]], [[ | | LMDDx = [[prostatic stromal sarcoma]], stromal nodule in [[benign prostatic hyperplasia]], [[leiomyosarcoma]], [[rhabdomyosarcoma]], [[sarcomatoid prostate carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = CD34 +ve, ER +ve, PR +ve, vimentin +ve, panker -ve{{fact}} | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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*[[Leiomyosarcoma]]. | *[[Leiomyosarcoma]]. | ||
*[[Rhabdomyosarcoma]]. | *[[Rhabdomyosarcoma]]. | ||
*[[Sarcomatoid prostate carcinoma]] - often associated with conventional prostate carcinoma & history of radiation. | |||
===Subclassification=== | ===Subclassification=== | ||
May be subclassified as per Gaudin ''et al.'':<ref name=pmid9500215>{{Cite journal | last1 = Gaudin | first1 = PB. | last2 = Rosai | first2 = J. | last3 = Epstein | first3 = JI. | title = Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases. | journal = Am J Surg Pathol | volume = 22 | issue = 2 | pages = 148-62 | month = Feb | year = 1998 | doi = | PMID = 9500215 }} | May be subclassified as per Gaudin ''et al.'':<ref name=pmid9500215>{{Cite journal | last1 = Gaudin | first1 = PB. | last2 = Rosai | first2 = J. | last3 = Epstein | first3 = JI. | title = Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases. | journal = Am J Surg Pathol | volume = 22 | issue = 2 | pages = 148-62 | month = Feb | year = 1998 | doi = | PMID = 9500215 }}</ref> | ||
</ref> | |||
#Scattered atypical cells with benign glands. | #Scattered atypical cells with benign glands. | ||
#Minimal atypical cells. | #Minimal atypical cells. | ||
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===Images=== | ===Images=== | ||
<gallery> | |||
Image: Prostatic stromal tumor of uncertain malignant potential - 1 WBAL.jpg | STUMP - 1 (WC/Netto) | |||
Image: Prostatic stromal tumor of uncertain malignant potential - 2 WBAL.jpg | STUMP - 2 (WC/Netto) | |||
</gallery> | |||
====www==== | |||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-138-11-1542-f01&doi=10.5858%2Farpa.2013-0212-RS STUMP (archivesofpathology.org)].<ref name=pmid25357117>{{Cite journal | last1 = Murer | first1 = LM. | last2 = Talmon | first2 = GA. | title = Stromal tumor of uncertain malignant potential of the prostate. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1542-5 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0212-RS | PMID = 25357117 }}</ref> | *[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-138-11-1542-f01&doi=10.5858%2Farpa.2013-0212-RS STUMP (archivesofpathology.org)].<ref name=pmid25357117>{{Cite journal | last1 = Murer | first1 = LM. | last2 = Talmon | first2 = GA. | title = Stromal tumor of uncertain malignant potential of the prostate. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1542-5 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0212-RS | PMID = 25357117 }}</ref> | ||
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*[[Prostate gland]]. | *[[Prostate gland]]. | ||
*[[Waffle diagnosis]]. | *[[Waffle diagnosis]]. | ||
*[[Smooth muscle tumour of uncertain malignant potential]]. | |||
==References== | ==References== |
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