48,720
edits
(6 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Prostatic stromal tumor of uncertain malignant potential - 1 WBAL.jpg | |||
| Width = | |||
| Caption = Prostatic stromal tumour of uncertain malignant potential. (WC/George Netto) | |||
| Synonyms = prostatic stromal proliferation of uncertain malignant potential | |||
| Micro = increased stromal cellularity, +/-nuclear atypia, +/-benign glands, lack small round blood vessels, no necrosis, no or minimal mitotic activity | |||
| Subtypes = | |||
| LMDDx = [[prostatic stromal sarcoma]], stromal nodule in [[benign prostatic hyperplasia]], [[leiomyosarcoma]], [[rhabdomyosarcoma]], [[sarcomatoid prostate carcinoma]] | |||
| Stains = | |||
| IHC = CD34 +ve, ER +ve, PR +ve, vimentin +ve, panker -ve{{fact}} | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[prostate gland]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = 20s-80s - typically 50s and 60s | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = usually good | |||
| Other = | |||
| ClinDDx = other tumours of the prostate, benign prostate, [[BPH]] | |||
| Tx = | |||
}} | |||
'''Prostatic stromal tumour of uncertain malignant potential''', abbreviated '''PSTUMP''', is a rare lesion of the prostatic stroma which cannot be definitively classified as benign or malignant. | '''Prostatic stromal tumour of uncertain malignant potential''', abbreviated '''PSTUMP''', is a rare lesion of the prostatic stroma which cannot be definitively classified as benign or malignant. | ||
Line 26: | Line 57: | ||
*[[Leiomyosarcoma]]. | *[[Leiomyosarcoma]]. | ||
*[[Rhabdomyosarcoma]]. | *[[Rhabdomyosarcoma]]. | ||
*[[Sarcomatoid prostate carcinoma]] - often associated with conventional prostate carcinoma & history of radiation. | |||
===Subclassification=== | ===Subclassification=== | ||
May be subclassified as per Gaudin ''et al.'':<ref name=pmid9500215>{{Cite journal | last1 = Gaudin | first1 = PB. | last2 = Rosai | first2 = J. | last3 = Epstein | first3 = JI. | title = Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases. | journal = Am J Surg Pathol | volume = 22 | issue = 2 | pages = 148-62 | month = Feb | year = 1998 | doi = | PMID = 9500215 }} | May be subclassified as per Gaudin ''et al.'':<ref name=pmid9500215>{{Cite journal | last1 = Gaudin | first1 = PB. | last2 = Rosai | first2 = J. | last3 = Epstein | first3 = JI. | title = Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases. | journal = Am J Surg Pathol | volume = 22 | issue = 2 | pages = 148-62 | month = Feb | year = 1998 | doi = | PMID = 9500215 }}</ref> | ||
</ref> | |||
#Scattered atypical cells with benign glands. | #Scattered atypical cells with benign glands. | ||
#Minimal atypical cells. | #Minimal atypical cells. | ||
Line 36: | Line 67: | ||
===Images=== | ===Images=== | ||
<gallery> | |||
Image: Prostatic stromal tumor of uncertain malignant potential - 1 WBAL.jpg | STUMP - 1 (WC/Netto) | |||
Image: Prostatic stromal tumor of uncertain malignant potential - 2 WBAL.jpg | STUMP - 2 (WC/Netto) | |||
</gallery> | |||
====www==== | |||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-138-11-1542-f01&doi=10.5858%2Farpa.2013-0212-RS STUMP (archivesofpathology.org)].<ref name=pmid25357117>{{Cite journal | last1 = Murer | first1 = LM. | last2 = Talmon | first2 = GA. | title = Stromal tumor of uncertain malignant potential of the prostate. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1542-5 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0212-RS | PMID = 25357117 }}</ref> | *[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-138-11-1542-f01&doi=10.5858%2Farpa.2013-0212-RS STUMP (archivesofpathology.org)].<ref name=pmid25357117>{{Cite journal | last1 = Murer | first1 = LM. | last2 = Talmon | first2 = GA. | title = Stromal tumor of uncertain malignant potential of the prostate. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1542-5 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0212-RS | PMID = 25357117 }}</ref> | ||
Line 48: | Line 84: | ||
*[[Prostate gland]]. | *[[Prostate gland]]. | ||
*[[Waffle diagnosis]]. | *[[Waffle diagnosis]]. | ||
*[[Smooth muscle tumour of uncertain malignant potential]]. | |||
==References== | ==References== |
edits