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Difference between revisions of "Molecular pathology"
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== | ==Polymerase chain reaction-based techniques== | ||
:Abbreviated ''PCR'''. | |||
===General=== | ===General=== | ||
*A molecular technique to duplicate DNA molecules ("amplify") and allow the DNA sequence to be determined. | |||
* | |||
Utility? | |||
*Detect very small molecular changes - submicroscopic. | |||
**Changes in sequence - may be as small as one base pair. | **Changes in sequence - may be as small as one base pair. | ||
*Used to confirmation [[chromosomal translocation]]s that are, in clinical practice, usually found with other techniques. | *Used to confirmation [[chromosomal translocation]]s that are, in clinical practice, usually found with other techniques. | ||