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Difference between revisions of "Robbins and Cotran 9th Edition Questions"
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Robbins and Cotran 9th Edition Questions (view source)
Revision as of 01:46, 19 May 2015
, 01:46, 19 May 2015→Chapter 1: The Cell as a Unit of Health and Disease
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{{hidden|Which CDKI's have selective effects on CDK4 and CDK6?|[[p15,p16,p17,and p19]]}} | {{hidden|Which CDKI's have selective effects on CDK4 and CDK6?|[[p15,p16,p17,and p19]]}} | ||
{{hidden| | {{hidden|List some examples of signal transduction pathways.|[[1) Receptor tyrosine kinases (RTKs), 2) Nonreceptor tyrosine kinase, 3) G-protein coupled receptors, 4) nuclear receptors, 5)Notch family receptors, 6) Wnt protein ligands (Frizzled family receptors).]]}} | ||
{{hidden|Why does nuclear beta catenin occur in some neoplasms?|[[When Wnt ligand bins to frizzled it recruits Disheveled, this leads to the disruption of the wnt-ubiquitin complex, this stabilized pool of b-catening is then translocated to the nucleus forming a transcriptional complex]]}} | |||
{{hidden|On Page 19 there is a table of growth factors involved in regeneration and repair, please review.|[[]]}} | |||
{{hidden|Describe the function of cadherin.|[[]]}} | |||
{{hidden|What are the functions of the extracellular matrix?|[[Mechanical support, control of cell proliferation, scaffolding for tissue renewal, establishment of tissue microenvironments]]}} | |||
{{hidden|What are the two basic forms of the ECM?|[[interstitial matrix (fibrillar and non fibrillar collagen, fibronectin, elastin, proteoglycans, hyloronate, and other stuff), basement membrane (type IV collagen and laminin) ]]}} | |||
{{hidden|What are the three proteins groups in the ECM?|[[1) fibrous structural proteins (collagen, elastins), 2) water hydrated gels (proteoglycans and hyaluronan), 3) adhesive glycoproteins (connect ECM to each other and other cells)]]}} | |||
{{hidden|Describe the structure of a protein that is dependent on vitamin C.|[[Collagen is composed of 3 seprate polypeptide chains braided into a rope like triple helix, lateral cross linking of the triple helices by lysyl oxidase (requires vitamin C) give it it's tensile strength. ]]}} | |||
{{hidden|List three non-fibrillar collagens.|[[Type IV -basement membrane, Type IX - Fibrillar associated collagen with interrupted triple helices (FACIT), Type VII (provides anchoring fibrils to basement membrane beneath skin)]]}} | |||
{{hidden|Which structural protein is associated with Marfan syndrom?|[[Fibrillin synthetic defects, which wrap the elastin core. ]]}} | |||
== Chapter 2 == | == Chapter 2 == | ||