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Difference between revisions of "Intraductal carcinoma of the prostate"
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Intraductal carcinoma of the prostate (view source)
Revision as of 05:04, 11 April 2015
, 05:04, 11 April 2015no edit summary
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| Caption = | | Caption = | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = ''major criteria'' : glands 2x normal (peripheral zone) glands, basal cells present, "cytologically malignant cells" (nuclear hyperchromasia, nuclear enlargement, nucleoli), fills the lumen ("expansile") but does not have to be "solid", +/-comedonecrosis; ''minor criteria'' : branching of ducts at right angles, rounded/smooth gland outlines, two cell populations (malignant appearing at periphery of gland, benign appearing - centre of gland) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = invasive [[prostatic carcinoma]], [[high grade prostatic intraepithelial neoplasia]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = CK34betaE12 +ve, p63 +ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 22: | Line 22: | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = uncommon | | Prevalence = uncommon | ||
| Bloodwork = | | Bloodwork = PSA typically elevated | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = | | Prognosis = poor, strongly suggestive invasion if not present | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = | ||